Clinical Epigenetic Society
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THE EDUCATION

Build your foundation.
Explore the evidence.

Online, self-paced education on DNA methylation, epigenetic clocks and biological aging—with context from CES faculty.

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A course designed
for focused learning.

Included with annual membership: Introduction to DNA Methylation, Epigenetic Clocks and Treatments.

8 course modulesOnline & self-pacedOne year of access

Who is it for?

Physicians, nurse practitioners, dietitians, clinical nutritionists and other health professionals interested in understanding the science behind epigenetic testing.

Course participation and professional credit eligibility are separate questions. Review the credit information.

COURSE CURRICULUM

Eight modules.
A foundation in epigenetics.

Follow the course from the history of biological aging clocks to epigenetic testing in clinical practice. Open each module to see its lessons.

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MODULE 01History of Biological Aging ClocksMike Stone, MD

Lessons in this module

  1. Introduction and welcome
  2. The importance of Biological Age
  3. Laying the Foundation
  4. Genetics Versus Epigenetics
  5. Environmental Influences
  6. Methylation As A Review
  7. Epigenetic Clock Generations
  8. Applications and More Future Directions
MODULE 02A Discovery That Reframes Healthcare: Clinical EpigeneticsJeff Bland, PhD

Lessons in this module

  1. Introduction and Overview
  2. Fundamental Concepts Underlying Biological Sciences
  3. The Birthing of a New Conceptual Framework for Health and Disease
  4. Emerging Technologies in Epigenetic Research
  5. Epigenetic Mechanisms in Disease Pathogenesis
  6. The Factors that Alter the Epigenome
  7. Epigenetics and Nutrition
  8. Epigenetics and the Immune System
  9. Successfully Personalizing the Approach
  10. Successfully Personalizing the Approach cont.
  11. EWAS
  12. Takeaways
MODULE 03Introduction to MethylationJeff Graham, MD

Lessons in this module

  1. Introduction to Methylation
  2. The Four Bases and Methylation
  3. Mechanisms of DNA Methylation
  4. Epigenetics Overview
  5. Types of Epigenetic Modifications
  6. DNA Methylation in Gene Regulation
  7. Clinical Applications of Methylation
  8. Summary and Key Takeaways
MODULE 04Biochemical versus DNA MethylationBridget Briggs, MD

Lessons in this module

  1. Introduction
  2. The Role of Methylation in Functional Genomics
  3. Understanding Genetics 101
  4. Introduction to Epigenetics
  5. Impact of Stress and Bonding on Methylation
  6. Impact of Medications and Lifestyle on Methylation
  7. Environmental Influences on Methylation
  8. Linking the Microbiome and the Methylome
  9. Methylomics and Predictive Medicine
  10. Epigenetic Mechanisms of Longevity
  11. Epigenetic Changes and Stress
  12. Methylation, Disease Prediction, and Hormone Therapy
  13. Estrabalome and its Impact on Methylation
  14. Methylation and Metabolic Gears
  15. Understanding MTHFR SNPs
  16. Personalized Plans Based on Genetic SNPs
  17. Future Interventions and Methylation Cases
MODULE 05Precision Aging: Using Omics & EMRs to Optimize Aging for Each IndividualJessica Lasky-Su, ScD

Lessons in this module

  1. How Do We Think about Aging?
  2. How Do We Think about Aging? (Part 2)
  3. Electronic Medical Records - Precision Aging
  4. Selecting Clinical Phenotypes
  5. A Robust and Reproducible Phenotype
  6. Clinical Relevance
  7. A Predictive Model
  8. The Complexity of Aging
  9. Creating OMICmAge
  10. OMICmAge Predictive Accuracy
  11. The Importance of OMICmAge
  12. Extending Our Understanding
MODULE 06Introduction to SymphonyAgeAlbert Higgins-Chen, MD, PhD & Raghav Sehgal, PhD

Lessons in this module

  1. Welcome and Introduction to SymphonyAge
  2. Existing Clocks & Development
  3. Defining Multiple Ages - Focusing on Organ Systems
  4. Training System Specific Scores
  5. The Power of Specificity
  6. From System Scores to Aging Subtypes
  7. From Biomarker to Anti-Aging Interventions
  8. SymphonyAge Caveat
MODULE 07Introduction to DunedinPACETerrie Moffitt, PhD

Lessons in this module

  1. How The Research Works
  2. The Theory & Methodology
  3. Defining Aging
  4. Measuring the Pace of Aging in a Longitudinal Study
  5. Validating the Pace of Aging Measurement
  6. Converting Pace of Aging into a Blood Test (Part 1)
  7. Converting Pace of Aging into a Blood Test (Part 2)
  8. Converting Pace of Aging into a Blood Test (Part 3)
  9. Validating the Blood Test
  10. Predictors of a Fast Pace of Aging
  11. Testing Treatments to Slow Pace of Aging
  12. Research Agenda Moving Forward
MODULE 08How to Use Epigenetic Testing in Your Clinical PracticeSanjeev Goel, MD

Lessons in this module

  1. Introduction to Epigenetic Testing
  2. Understanding Biological Age and Its Importance
  3. Diving into OMICAge and Its Clinical Relevance
  4. Symphony Age: A New Perspective on Organ Aging
  5. Dunedin Pace: Measuring the Speed of Aging
  6. The Role of CRP in Inflammation and Aging
  7. Summary of Epigenetic Biomarkers and Their Applications

COURSE FACULTY

People behind
the perspectives.

Learn from the educators and researchers who teach the eight course modules.

Jeff Bland, PhD

Jeff Bland, PhD

Clinical epigenetics

The field’s foundations and its perspective on healthcare.

Course contribution

Teaches Module 2: A Discovery That Reframes Healthcare: Clinical Epigenetics. Lessons include epigenetics and nutrition, the immune system, and personalizing the approach.

Terrie Moffitt, PhD

Terrie Moffitt, PhD

DunedinPACE

The research behind measuring the pace of aging.

Course contribution

Teaches Module 7: Introduction to DunedinPACE. Lessons cover longitudinal measurement, validation and converting pace of aging into a blood test.

Mike Stone, MD

Mike Stone, MD

History of biological aging clocks

The questions and methods that shaped aging measurement.

Course contribution

Teaches Module 1: History of Biological Aging Clocks. Lessons introduce biological age, genetics versus epigenetics, environmental influences and clock generations.

Selected portraits shown. The remaining course faculty are listed below.

Jeff Graham, MD

Module 3 · Introduction to Methylation

Bridget Briggs, MD

Module 4 · Biochemical versus DNA Methylation

Jessica Lasky-Su, ScD

Module 5 · Precision Aging: Using Omics & EMRs

Albert Higgins-Chen, MD, PhD

Module 6 · Introduction to SymphonyAge

Raghav Sehgal, PhD

Module 6 · Introduction to SymphonyAge

Sanjeev Goel, MD

Module 8 · Epigenetic Testing in Clinical Practice

Learn on your schedule.
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Membership brings the course and CES online forum together for one year.

Start with foundations

Build familiarity with the concepts before exploring individual tools.

Return to the research

Consider the questions, methods and limitations behind a result.

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Use the online forum to exchange ideas and questions with the community.

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See what is included, annual pricing and practical enrollment questions.

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